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Development of a tube nebulizer for microflow atmospheric pressure chemical ionization mass spectrometry
Strmeň, Timotej ; Vrkoslav, Vladimír ; Pačes, Ondřej ; Cvačka, Josef
A novel nebulizer for microflow atmospheric pressure chemical ionization mass spectrometry was developed. It consisted of a tube with analyte-transporting fused silica capillary inside. The terminal part of the tube was resistively heated using a coiled resistance wire. Optimal nebulizer parameters and construction setup were investigated to fully demonstrate its versability. Corundum appeared to be a more suitable material than quartz for fabrication of the tube nebulizer. The lowest analyte flow rate investigated was 1.0 mul/min with an excellent signal stability reached.

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